Gastrointestinal

The complications that Treacher Collins Syndrome patients face with feeding and nutritional deficits can lead to:

Complications of cryptorchidism includes:

• Constipation

• Diarrhea

• belly pain.

• Gastroesophageal reflux

• regurgitation

It has been proven, through animal models, the role of TCOF1 gene in ganglionic cell migration of the foregut.

The failure of migration of these ganglionic cells can lead to a decrease in gastric motility.